21c Museum Hotel St. Louis

1528 Locust street, St. Louis, MO 63103 US near Exit 39b on I-64 (~0.5mi)
View Map Reservations: +1-800-219-2797
4.5 Star Property Near St. Louis Union Station
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Select My Room
  • Free WiFi
  • Number of indoor pools - 1
  • Breakfast available (surcharge)
  • Fitness facilities
  • Pool hoist on site
  • Wheelchair-accessible pool
  • Stair-free path to entrance
  • Billiards or pool table
  • Smoke-free property
Select Your Room:
09/07/2024 - 09/08/2024
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Standard prices by room type for the next 60 days

Rates shown are nightly rates before taxes and do not necessarily reflect all discounts available. The chart provides the cheapest public rates available by room type.

Property Description

A stay at 21C Museum Hotel St Louis places you in the heart of St. Louis, within a 10-minute walk of City Museum and Enterprise Center. This luxury hotel is 0.6 mi (1 km) from St. Louis Union Station and 0.7 mi (1.1 km) from America's Center Convention Complex.

Enjoy a meal at the restaurant or snacks in the coffee shop/cafe. The hotel also offers room service (during limited hours). Quench your thirst with your favorite drink at the bar/lounge. Cooked-to-order breakfasts are available daily from 6:30 AM to 1:00 PM for a fee.

Make yourself at home in one of the 104 air-conditioned rooms featuring espresso makers and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms have complimentary toiletries and hair dryers. Conveniences include phones, as well as safes and desks.

Distances are displayed to the nearest 0.1 mile and kilometer.

Campbell House Museum - 0.1 km / 0.1 mi
Washington Avenue Historic District - 0.3 km / 0.2 mi
Central Public Library - 0.3 km / 0.2 mi
Peabody Opera House - 0.5 km / 0.3 mi
City Museum - 0.5 km / 0.3 mi
Enterprise Center - 0.6 km / 0.4 mi
St. Louis City Hall - 0.7 km / 0.4 mi
St. Louis Aquarium at Union Station - 0.8 km / 0.5 mi
St. Louis Union Station - 1 km / 0.6 mi
St. Louis Union Station Mini Golf - 1.1 km / 0.7 mi
America's Center Convention Complex - 1.1 km / 0.7 mi
National Blues Museum - 1.3 km / 0.8 mi
Kiener Plaza - 1.4 km / 0.9 mi
Dome at America’s Center - 1.5 km / 0.9 mi
Gateway Arch National Park - 1.5 km / 0.9 mi

The nearest airports are:
St. Louis Lambert Intl. Airport (STL) - 29.5 km / 18.4 mi
St. Louis, MO (SUS-Spirit of St. Louis) - 41.6 km / 25.8 mi

Featured amenities include a business center, dry cleaning/laundry services, and a 24-hour front desk.

Don't miss out on the many recreational opportunities, including an indoor pool, a steam room, and a fitness center. Additional amenities at this hotel include complimentary wireless internet access, concierge services, and a vending machine.

Amenities / Features

  • Check In: 4:00 PM
  • Check Out: 11:00 AM
  • Minimum age of oldest guest: 21
  • Dry cleaning/laundry service
  • Biodegradable/compostable stirrers
  • No single-use plastic straws
  • No single-use plastic soda bottles
  • No single-use plastic stirrers
  • Reusable cups only
  • Reusable tableware only
  • Biodegradable/compostable straws
  • No single-use plastic water bottles
  • Free WiFi
  • Number of bars/lounges - 1
  • Braille or raised signage
  • Number of indoor pools - 1
  • Wheelchair-accessible lounge
  • No accessible shuttle
  • Wheelchair-accessible on-site restaurant
  • Visual alarms in hallways
  • Handrails in stairways
  • Wheelchairs available on site
  • Breakfast available (surcharge)
  • Number of coffee shops/cafes - 1
  • Elevator
  • Fitness facilities
  • Wheelchair accessible (may have limitations)
  • Vending machine
  • Change of bed sheets (on request)
  • Wheelchair-accessible spa
  • Total number of rooms - 104
  • Professional property host/manager
  • LGBTQ friendly
  • No cribs (infant beds) available
  • No rollaway/extra beds available
  • Pool hoist on site
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible fitness center
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Well-lit path to entrance
  • Change of towels (on request)
  • Stair-free path to entrance
  • Registration desk height (centimeters) - 91
  • Elevator door width (inches) - 42
  • Registration desk height (inches) - 36
  • Stairwell handrail height (inches) - 36
  • Elevator door width (centimeters) - 107
  • Luggage storage
  • Billiards or pool table
  • Stairwell handrail height (centimeters) - 91
  • Business center
  • 24-hour front desk
  • Number of restaurants - 1
  • Spa services on site
  • Smoke-free property
  • Steam room
  • Valet parking (surcharge)
  • Wheelchair accessible path of travel
  • ATM/banking
  • Concierge services

Pet Friendly?

Service animals complying with ADA Title lll regulations are allowed.

Service animals are allowed

Service animals are exempt from fees/restrictions

Only dogs are allowed

Pets allowed

Misc Fees / Policies

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 45 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You'll be asked to pay the following charges at the property:

  • Service fee: USD 5 per accommodation, per stay

We have included all charges provided to us by the property.

  • Reservations are required for massage services. Reservations can be made by contacting the hotel prior to arrival, using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Cleaning Policies

Property is cleaned with disinfectant

Bed sheets and towels are washed at a temperature of at least 60°C/140°F

Commonly-touched surfaces are cleaned with disinfectant

Property confirms they are implementing enhanced cleaning measures